From Reuters/Yahoo today..

NEW YORK (Reuters Health) -Low doses of pamidronate increase bone mineral density (BMD) in children with spastic cerebral palsy with severe movement impairment, according to results of a preliminary study reported in Developmental Medicine and Child Neurology.

All of the children had spastic quadriplegia, a severe form of cerebral palsy characterized by muscle stiffness in all four limbs, the trunk and often the mouth and tongue. These patients often have mental retardation and other problems. The decreased mobility seen in these children leads to bone loss, which puts them at high risk for fractures.

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Tags: quadriplegia