Cerebral palsy is the fourth leading cause of paralysis in the United States, according to a new report by the Christopher and Dana Reeve Foundation. The report estimated that about 412,000 of the more than five million cases of paralysis in the U.S. are due to cerebral palsy.

What is cerebral palsy? Cerebral palsy is a movement disorder that can cause spasticity, paralysis or limpness in the arms and legs – sometimes the condition only affects one side or half of the body, and other times it affects all limbs.

Cerebral palsy is generally caused by brain damage and is diagnosed in thousands of infants and children each year. As with spinal cord injuries, there is no cure for cerebral palsy. However, extensive research efforts are being made to change this.

The top three causes of paralysis include stroke, spinal cord injury (which Christopher Reeve suffered) and multiple sclerosis. Additional causes include traumatic brain injury and birth defects.

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